We are releasing all PrediXcan associations based on Neale Lab’s UKB rapid GWAS results

Published

October 15, 2017

Update (11/1/2017)

Gene level results “meta analyzed” across tissues now available.
Shinyapp to directly query by gene and phenotype is here but can be slow. Stay tuned for faster version coming soon.

As many of you may know, Neale Lab made a big splash in the GWAS community by releasing the summary results of 2400+ phenotypes from the UK Biobank. Following their lead on open science and open data sharing, we are releasing the bulk runs of PrediXcan association based on Neale Lab’s UKB results and 44 tissues models from GTEx V6p release.

All PrediXcan associations can be downloaded from here

We are also generating a “meta analyzed” across tissues version, which we find much more easily interpretable. They will be uploaded within the next few days.

All this is work in progress, so feedback is greatly appreciated! We are trying to flag some suspicous results (likely false positives) but so please let us know if you find them.

A Web app for query (Shinyapp) will be rolled out shortly, so stay tuned.